If your doctor has detected consistently elevated PSA (prostate-specific antigen) levels over a period of years or tests, a prostate biopsy is recommended. Before doing so, your doctor should have conducted a digital rectal exam (DRE) to feel for any abnormalities that could be caused by tumor growth. A transrectal ultrasound may have also been used to create an image of your prostate. A prostate cancer expert, proficient in diagnosis and treatment, should review the results of these tests.
When substantial evidence exists suggesting the possibility of cancer, a prostate biopsy is used to sample the prostate tissue. These tissue samples provide a clearer diagnosis and help doctors determine the grade, or Gleason Score, of your prostate cancer.